PACT & related publications


Professor Jonathan Green's blog


Green, J., Pickles, A., Pasco, G., Bedford, R., Wan, M. W., Elsabbagh, M., ... & Charman, T. (2017). Randomised trial of a parent‐mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years. Journal of Child Psychology and Psychiatry 



Rahman, A., Divan, G., Hamdani, S. U., Vajaratkar, V., Taylor, C., Leadbitter, K., ... Green, J.  (2016). Effectiveness of the parent-mediated intervention for children with autism spectrum disorder in south Asia in India and Pakistan (PASS): a randomised controlled trial. The Lancet Psychiatry, 3(2), 128-136.  PMID:


Wan, M. W., Brooks, A., Green, J., Abel, K., & Elmadih, A. (2016). Psychometrics and validation of a brief rating measure of parent-infant interaction Manchester assessment of caregiver–infant interaction. International Journal of Behavioral Development, 1-8.  DOI:


Pickles, A., Le Couteur, A., Leadbitter, K., Salomone, E., Cole-Fletcher, R., Tobin, H., ... & Aldred, C. (2016). Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomised controlled trial. The Lancet, 388(10059), 2501-2509. 



Divan, G., Hamdani, S. U., Vajartkar, V., Minhas, A., Taylor, C., Aldred, C., ... Patel, V. (2015). Adapting an evidence-based intervention for autism spectrum disorder for scaling up in resource-constrained settings: the development of the PASS intervention in South Asia. Global health Action, vol 8.   PMID:


Elsabbagh, M., Bruno, R., Wan, M. W., Charman, T., Johnson, M. H., Green, J., & The BASIS Team. (2015). Infant neural sensitivity to dynamic eye gaze relates to quality of parent–infant interaction at 7-months in infants at risk for autism. Journal of Autism and Developmental Disorders45(2), 283-291.  PMID:


Green, J. (2015). Editorial: Process to progress? Investigative trials, mechanism and clinical science. Journal of Child Psychology and Psychiatry56(1), 1-3.  PMID:


Green, J., Charman, T., Pickles, A., Wan, M. W., Elsabbagh, M., Slonims, V., … & The BASIS Team.  (2015). Parent-mediated intervention versus no intervention for infants at high risk of autism: a parallel, single-blind, randomised trial. The Lancet Psychiatry2(2), 133-140.  PMID: 


Green, J. M., (2015) Relationship-based treatments. In A. Thapar, D. S. Pine, J. F.  Leckman, S. Scott, M. J. Snowling & E. Taylor (Eds.), Rutter's Child and Adolescent Psychiatry, (pp 521-532). Oxford:   Wiley Blackwell.  DOI:



De Rubeis, S., He, X., Goldberg, A. P., Poultney, C. S., Samocha, K., Cicek, A. E., ... Singh, T. (2014). Synaptic, transcriptional and chromatin genes disrupted in autism. Nature515(7526), 209-215.  PMID:


Harrop, C., McConachie, H., Emsley, R., Leadbitter, K., Green, J., & The PACT Consortium. (2014). Restricted and repetitive behaviors in autism spectrum disorders and typical development: Cross-sectional and longitudinal comparisons. Journal of Autism and Developmental Disorders44(5), 1207-1219.  PMID:


McConachie, H., & Fletcher‐Watson, S. et al. (2014). Building capacity for rigorous controlled trials in autism: the importance of measuring treatment adherence.  Child: Care, Health and Development41(2), 169-177.  PMID:


Pickles, A., Harris, V., Green, J., Aldred, C., McConachie, H., Slonims, V., ... Charman, T. (2014).  Treatment mechanism in the MRC preschool autism communication trial: implications for study design and parent‐focussed therapy for children. Journal of Child Psychology and Psychiatry, 56(2), 162-170.  PMID:


Pinto, D., Delaby, E., Merico, D., Barbosa, M., Merikangas, A., Klei, L., ... Vorstman, J. A. (2014). Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. The American Journal of Human Genetics94(5), 677-694.  PMID:



Green, J., Wan, M. W., Guiraud, J., Holsgrove, S., McNally, J., Slonims, V., ... Johnson, M. (2013). Intervention for infants at risk of developing autism: a case series. Journal of Autism and Developmental Disorders,43(11), 2502-2514. PMID:


Hudry, K., Aldred, C., Wigham, S., Green, J., Leadbitter, K., Temple, K., ... McConachie, H. (2013). Predictors of parent–child interaction style in dyads with autism. Research in Developmental Disabilities34(10), 3400-3410.  PMID:


Kendall, T., et al., (2013) Management of autism in children and young people: summary of NICE and SCIE guidance.  BMJ (Clinical research ed.), 347:f4865.  PMID:


Wan, M. W., Green, J., Elsabbagh, M., Johnson, M., Charman, T., Plummer, F. & The BASIS Team.  (2013). Quality of interaction between at‐risk infants and caregiver at 12–15 months is associated with 3‐year autism outcome.  Journal of Child Psychology and Psychiatry54(7), 763-771.  PMID:



Aldred, C., Green, J., Emsley, R., & McConachie, H. (2012). Brief report: Mediation of treatment effect in a communication intervention for pre-school children with autism. Journal of Autism and Developmental Disorders42(3), 447-454. PMID:


Barrett, B., Byford, S., Sharac, J., Hudry, K., Leadbitter, K., Temple, K., Aldred, C., Slonims, V., Green, J. ... & PACT Consortium. (2012). Service and wider societal costs of very young children with autism in the UK. Journal of Autism and Developmental Disorders42(5), 797-804.  PMID:


Wan, M. W., Green, J., Elsabbagh, M., Johnson, M., Charman, T., Plummer, F., & The BASIS Team. (2012). Parent–infant interaction in infant siblings at risk of autism. Research in Developmental Disabilities33(3), 924-932.  PMID:  



Green, J., (2011). Early communication-focused parenting interventions for autism.  Child and Adolescent Mental Health, 16(1), 34.  Publication link:


Green, J., Charman, T., Mc Conachie, H., Aldred, C., Slonims, V., Howlin, P., ... & The PACT Consortium  (2011). FC14-05 - Parent-mediated communication-focused treatment for preschool children with autism (MRC PACT); a randomised controlled trial. European Psychiatry26, 1897. DOI:



Clifford, S., Hudry, K., Brown, L., Pasco, G., Charman, T., & The PACT Consortium. (2010).  The modified-classroom observation schedule to measure intentional communication (M-COSMIC): evaluation of reliability and validity. Research in Autism Spectrum Disorders4(3), 509-525.  DOI:


Green, J., Charman, T., McConachie, H., Aldred, C., Slonims, V., Howlin, P., ... & The PACT Consortium. (2010). Parent-mediated communication-focused treatment in children with autism (PACT): a randomised controlled trial. The Lancet375(9732), 2152-2160.  PMID:


Hudry, K., Leadbitter, K., Temple, K., Slonims, V., McConachie, H., Aldred, C., Howlink, P., Charman, T. and The PACT Consortium.  (2010). Preschoolers with autism show greater impairment in receptive compared with expressive language abilities. International Journal of Language & Communication Disorders45(6), 681-690.  PMID: