Disadvantages and risks

We have extensive experience of all our research tests and procedures and all have been used on very large numbers of patients in the UK and world-wide. It is essential that people find them acceptable otherwise research would fail. Nevertheless, it is possible you might find some questions too personal, upsetting or tiresome. If you do, we will treat this with respect and understanding. If you are currently undergoing treatment, this study does not include any changes to this and it should not have a negative impact on your mental health in any way.

Blood and DNA sample

Some people feel mild discomfort when giving a blood sample. Sometimes there is mild bruising afterwards.

As we are taking a blood sample for genetic analysis, very rarely we may find a genetic risk factor which may have important implications for your future health or for the health of your family. In these rare circumstances, we will take advice from a clinical geneticist (a specialist in this area) who may advise us to re-contact you and/or your GP. In this case you may be offered the option to seek further advice through a genetic counselling service. However, there will be a space on the consent form for you to let us know if you would prefer for us not to contact you about such findings. If you don’t want us to inform you of any findings, we would not contact your GP either. 

MRS

The MRI scanner uses a large magnet to take pictures and there are no known risks unless you have any metal in your body which might be affected by the magnet. A checklist will be given to rule out the presence of metal objects. Some people can find the MRI scanner claustrophobic – reassurance will be provided and staff will be there for support. You can also stop the scan at any time.

For study site specific risks, please select the site closest to you: