The development of new experimental methodologies to quantify bio-mechanical properties at microscopic length scales is essential to understanding the link between molecular structure and whole-tissue mechanics. Such methodologies would make major contributions to our knowledge of age-related pathologies of elastic tissues, such as the lungs, vasculature, cartilage and skin.
There are two main research areas:
- Nano-indentation of cryo-preserved tissues
- Scanning acoustic microscopy of cryo-preserved tissues