Publications

  • 2014

    Article

  • 2013

    Article

    • Avatapalle, H. B., Banerjee, I., Shah, S., Pryce, M., Nicholson, J., Rigby, L., ... Clayton, P. E. (2013). Abnormal neurodevelopmental outcomes are common in children with transient congenital hyperinsulinism. Frontiers in Endocrinology, 4(MAY), [Article 60]. DOI: 10.3389/fendo.2013.00060. Publication link: de272edc-9b16-40af-9338-dc5501ea29c0 | PubMed:23730298
    • Banerjee, I., Avatapalle, B., Padidela, R., Stevens, A., Cosgrove, K. E., Clayton, P. E., & Dunne, M. J. (2013). Integrating genetic and imaging investigations into the clinical management of congenital hyperinsulinism. Clinical Endocrinology, 78(6), 803-813. DOI: 10.1111/cen.12153. Publication link: 60ea2c51-cc57-4569-b2a5-82cef7e2a125 | PubMed:23347463
    • Clayton, P., Bonnemaire, M., Dutailly, P., Maisonobe, P., Naudin, L., Pham, E., ... Albanese, A. (2013). Characterizing short stature by insulin-like growth factor axis status and genetic associations: Results from the prospective, cross-sectional, epidemiogenetic EPIGROW study. Journal of Clinical Endocrinology and Metabolism, 98(6), E1122-E1130. DOI: 10.1210/jc.2012-4283. Publication link: d923f8db-b4e4-402a-97c6-d78b56ebc186 | PubMed:23596138
    • Clayton, P., Chatelain, P., Tato, L., Yoo, H. W., Ambler, G. R., Belgorosky, A., ... Olivier, C. (2013). A pharmacogenomic approach to the treatment of children with GH deficiency or Turner syndrome. European Journal of Endocrinology, 169(3), 277-289. DOI: 10.1530/EJE-13-0069. Publication link: bffdddc5-910d-4a93-a0b0-6ef48882837f | PubMed:23761422
    • Clayton, P., Poole, R. L., Docherty, L. E., Al Sayegh, A., Caliebe, A., Turner, C., ... Mackay, D. J. G. (2013). Targeted methylation testing of a patient cohort broadens the epigenetic and clinical description of imprinting disorders. American Journal of Medical Genetics, Part A, 161(9), 2174-2182. DOI: 10.1002/ajmg.a.36049. Publication link: d97f5c3d-ac19-48b9-b96d-8a3da9ebe0dc | PubMed:23913548
    • Downing, J., Gleeson, H. K., Clayton, P. E., Davis, J. R. E., Wales, J. K., & Callery, P. (2013). Transition in endocrinology: The challenge of maintaining continuity. Clinical Endocrinology, 78(1), 29-35. DOI: 10.1111/j.1365-2265.2012.04473.x. Publication link: 81c9a368-05fc-4de1-bc80-44362dc8d53e | PubMed:22734661
    • Flanagan, S. E., Xie, W., Caswell, R., Damhuis, A., Vianey-Saban, C., Akcay, T., ... Ellard, S. (2013). Next-generation sequencing reveals deep intronic cryptic ABCC8 and HADH splicing founder mutations causing hyperinsulinism by pseudoexon activation. American Journal of Human Genetics, 92(1), 131-136. DOI: 10.1016/j.ajhg.2012.11.017. Publication link: 5c65ea04-e70f-4cb0-8114-87b4cbcdebf0 | PubMed:23273570
    • Gleeson, H., Davis, J., Jones, J., O'Shea, E., & Clayton, P. E. (2013). The challenge of delivering endocrine care and successful transition to adult services in adolescents with congenital adrenal hyperplasia: Experience in a single centre over 18 years. Clinical Endocrinology, 78(1), 23-28. DOI: 10.1111/cen.12053. Publication link: 0ad75418-5f2a-4901-a2e6-582fc7d6210a | PubMed:23009615
    • Jenkinson, E. M., Rehman, A. U., Walsh, T., Clayton-Smith, J., Lee, K., Morell, R. J., ... Newman, W. G. (2013). Perrault syndrome is caused by recessive mutations in CLPP, encoding a mitochondrial ATP-dependent chambered protease. American Journal of Human Genetics, 92(4), 605-613. DOI: 10.1016/j.ajhg.2013.02.013. Publication link: ee3718e3-9d25-4e36-8fd6-0fe8cc104895 | PubMed:23541340
    • Kendall, D., Vail, A., Amin, R., Barrett, T., Dimitri, P., Ivison, F., ... Hall, C. (2013). Metformin in obese children and adolescents: The MOCA trial. Journal of Clinical Endocrinology and Metabolism, 98(1), 322-329. DOI: 10.1210/jc.2012-2710. Publication link: e2ccd453-b063-46da-ae58-51cd6a4887d3 | PubMed:23175691
    • Marshall, M., Gidman, W., & Callery, P. (2013). Supporting the care of children with diabetes in school: A qualitative study of nurses in the UK. Diabetic Medicine, 30(7), 871-877. DOI: 10.1111/dme.12154. Publication link: 0d86bde0-dad9-4389-a435-409bd303d429
    • Murray, P. G., Hanson, D., Coulson, T., Stevens, A., Whatmore, A., Poole, R. L., ... Clayton, P. E. (2013). 3-M syndrome: a growth disorder associated with IGF2 silencing.Endocrine Connections, 2(4). DOI: 10.1530/EC-13-0065. Publication link: 0da0e1b1-34f2-4195-9727-848841659ef6 | PubMed:24148222
    • Ramachandrappa, S., Raimondo, A., Cali, A. M. G., Keogh, J. M., Henning, E., Saeed, S., ... Farooqi, I. S. (2013). Rare variants in single-minded 1 (SIM1) are associated with severe obesity. Journal of Clinical Investigation, 123(7), 3042-3050. DOI: 10.1172/JCI68016. Publication link: 2f84ab42-aba7-470f-b2b7-3b5e313442f2 | PubMed:23778139
    • Sergijenko, A., Langford-Smith, A., Liao, A. Y., Pickford, C. E., McDermott, J., Nowinski, G., ... Bigger, B. W. (2013). Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease. Molecular Therapy, 21(10), 1938-1949. DOI: 10.1038/mt.2013.141. Publication link: 92d80ae2-89e6-48eb-a53c-d742191871c8 | PubMed:23748415
    • Stevens, A., Cosgrove, K. E., Padidela, R., Skae, M. S., Clayton, P. E., Banerjee, I., & Dunne, M. J. (2013). Can network biology unravel the aetiology of congenital hyperinsulinism?Orphanet Journal of Rare Diseases, 8(1), [21]. DOI: 10.1186/1750-1172-8-21. Publication link: 82e47a9c-efd0-4067-87a8-a7966970b775 | PubMed:23394473
    • Stevens, A., De Leonibus, C., Hanson, D., Dowsey, A. W., Whatmore, A., Meyer, S., ... Dunne, M. J. (2013). Network analysis: A new approach to study endocrine disorders. Journal of molecular endocrinology, 52(1), R79-R93. DOI: 10.1530/JME-13-0112. Publication link: 76b2bc5c-0d1b-409a-bc63-d7e47bba34f2 | PubMed:24085748
    • Stevens, A., Hanson, D., Whatmore, A., Destenaves, B., Chatelain, P., & Clayton, P. (2013). Human growth is associated with distinct patterns of gene expression in evolutionarily conserved networks. BMC Genomics, 14(1), [547]. DOI: 10.1186/1471-2164-14-547. Publication link: 7256a621-f941-4bc5-bc8f-76ba0251c184 | PubMed:23941278
    • White, D. J., Unwin, R. D., Bindels, E., Pierce, A., Teng, H. Y., Muter, J., ... Meyer, S. (2013). Phosphorylation of the Leukemic Oncoprotein EVI1 on Serine 196 Modulates DNA Binding, Transcriptional Repression and Transforming Ability. PLoS ONE, 8(6), [e66510]. DOI: 10.1371/journal.pone.0066510. Publication link: 5cd1e4d9-b867-410f-9626-325469e59bd5 | PubMed:23776681
    • Wit, J. M., Ranke, M. B., Albertsson-Wikland, K., Carrascosa, A., Rosenfeld, R. G., Van Buuren, S., ... Roelants, M. (2013). Personalized approach to growth hormone treatment: Clinical use of growth prediction models. Hormone Research in Paediatrics, 79(5), 257-270. DOI: 10.1159/000351025. Publication link: 5195513f-201f-46f2-998d-1a42df787d5f | PubMed:23735882
  • 2012

    Article

    • Ayoola, O. O., Whatmore, A., Balogun, W. O., Jarrett, O. O., Cruickshank, J. K., & Clayton, P. E. (2012). Maternal malaria status and metabolic profiles in pregnancy and in cord blood: Relationships with birth size in Nigerian infants. Malaria Journal, 11, [75]. DOI: 10.1186/1475-2875-11-75. Publication link: b30c3eb4-88a5-41a9-9bec-c7998034f70b | PubMed:22429464
    • Banerjee, I., Avatapalle, B., Petkar, A., Skae, M., Padidela, R., Ehtisham, S., ... Clayton, P. E. (2012). The association of cardiac ventricular hypertrophy with congenital hyperinsulinism. European Journal of Endocrinology, 167(5), 619-624. DOI: 10.1530/EJE-12-0632. Publication link: c0543880-843a-48f1-9bc2-e94d700ff3c5 | PubMed:22894813
    • Bray, L., Callery, P., & Kirk, S. (2012). A qualitative study of the pre-operative preparation of children, young people and their parents' for planned continence surgery: Experiences and expectations. Journal of Clinical Nursing, 21(13-14), 1964-1973. DOI: 10.1111/j.1365-2702.2011.03996.x. Publication link: 54dc3da6-65e3-410a-8a4d-bdd2937799a9
    • Clayton, P. E., Hanson, D., Magee, L., Murray, P. G., Saunders, E., Abu-Amero, S. N., ... Black, G. C. M. (2012). Exploring the spectrum of 3-M syndrome, a primordial short stature disorder of disrupted ubiquitination. Clinical Endocrinology, 77(3), 335-342. DOI: 10.1111/j.1365-2265.2012.04428.x. Publication link: 6a3b5baf-b5e7-44ec-9f07-79f372aa720d | PubMed:22624670
    • Hanson, D., Murray, P. G., Coulson, T., Sud, A., Omokanye, A., Stratta, E., ... Clayton, P. E. (2012). Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.Journal of molecular endocrinology, 49(3), 267-275. DOI: 10.1530/JME-12-0034. Publication link: 6982ff5b-4557-4218-a727-7a53a4be9ac8 | PubMed:23018678
    • Lee, L. M. Y., Leung, C. Y., Tang, W. W. C., Choi, H. L., Leung, Y. C., McCaffery, P. J., ... Shum, A. S. W. (2012). A paradoxical teratogenic mechanism for retinoic acid. Proceedings of the National Academy of Sciences of the United States of America, 109(34), 13668-13673. DOI: 10.1073/pnas.1200872109. Publication link: 37b980a0-6c8e-45c6-95cd-d6aed07ac4ac
    • Mccabe, M., Jones, D. T. W., Jäger, N., Kool, M., Zichner, T., Hutter, B., ... Lichter, P. (2012). Dissecting the genomic complexity underlying medulloblastoma. Nature, 487(7409), 100-105. DOI: 10.1038/nature11284. Publication link: d007a7b0-8d3b-4d73-851b-cb8906f6a391
    • Patel, L., & Clayton, P. E. (2012). Predicting response to growth hormone treatment. Indian Journal of Pediatrics, 79(2), 229-237. DOI: 10.1007/s12098-011-0611-x. Publication link: 9249fd53-2d53-437b-aa0e-db8783023480 | PubMed:22105236
    • Pitera, J. E., Woolf, A. S., Albert Basson, M., & Scambler, P. J. (2012). Sprouty1 haploinsufficiency prevents renal agenesis in a model of Fraser syndrome. Journal of the American Society of Nephrology, 23(11), 1790-1796. DOI: 10.1681/ASN.2012020146. Publication link: 61d242a2-9f8c-4561-819a-8d6a552b4feb
    • Renehan, A. G., Solomon, M., Zwahlen, M., Morjaria, R., Whatmore, A., Audí, L., ... Clayton, P. E. (2012). Growth hormone receptor polymorphism and growth hormone therapy response in children: A bayesian meta-analysis. American Journal of Epidemiology, 175(9), 867-877. DOI: 10.1093/aje/kwr408. Publication link: 7c65615c-525b-4be6-a6f3-661aa3f98a9a | PubMed:22494952
    • Rosenfeld, R. G., Cohen, P., Robison, L. L., Bercu, B. B., Clayton, P., Hoffman, A. R., ... Wit, J. M. (2012). Long-term surveillance of growth hormone therapy. Journal of Clinical Endocrinology and Metabolism, 97(1), 68-72. DOI: 10.1210/jc.2011-2294. Publication link: 602f7391-e12d-47da-a1de-193a65641223 | PubMed:22174422
    • Wu, X., Northcott, P. A., Dubuc, A., Dupuy, A. J., Shih, D. J. H., Witt, H., ... Taylor, M. D. (2012). Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature, 482(7386), 529-533. DOI: 10.1038/nature10825. Publication link: e3ad1e88-1114-4d67-a539-b44129c834ee
  • 2011

    Article

    • Ayoola, O. O., Gemmell, I., Omotade, O. O., Adeyanju, O. A., Cruickshank, J. K., & Clayton, P. E. (2011). Maternal malaria, birth size and blood pressure in nigerian newborns: Insights into the developmental origins of hypertension from the ibadan growth cohort. PLoS ONE, 6(9), [e24548]. DOI: 10.1371/journal.pone.0024548. Publication link: 5183a3d9-0a18-4599-b2b0-2cc12acac2f1 | PubMed:21931749
    • Banerjee, I., Skae, M., Flanagan, S. E., Rigby, L., Patel, L., Didi, M., ... Clayton, P. E. (2011). The contribution of rapid KATP channel gene mutation analysis to the clinical management of children with congenital hyperinsulinism. European Journal of Endocrinology, 164(5), 733-740. DOI: 10.1530/EJE-10-1136. Publication link: 735bc2e7-bd84-48a0-962f-504dfcc534d8 | PubMed:21378087
    • Bansal, N., Anderson, S. G., Vyas, A., Gemmell, I., Charlton-Menys, V., Oldroyd, J., ... Cruickshank, J. K. (2011). Adiponectin and lipid profiles compared with insulins in relation to early growth of British South Asian and European children: The manchester children's growth and vascular health study. Journal of Clinical Endocrinology and Metabolism, 96(8), 2567-2574. DOI: 10.1210/jc.2011-0046. Publication link: c19a1d05-1b8e-4935-a3c6-3f688c171dc7 | PubMed:21632814
    • Clayton, P. E., Banerjee, I., Murray, P. G., & Renehan, A. G. (2011). Growth hormone, the insulin-like growth factor axis, insulin and cancer risk. Nature Reviews Endocrinology, 7(1), 11-24. DOI: 10.1038/nrendo.2010.171. Publication link: eba770f0-8b36-4989-9d9b-aa13a894ece4 | PubMed:20956999
    • Clayton, P., & Clemmons, D. R. (2011). Consensus statement on the standardization and evaluation of growth hormone and insulin-like growth factor assays. Clinical Chemistry, 57(4), 555-559. DOI: 10.1373/clinchem.2010.150631. Publication link: 036b5639-e471-4bb1-ab08-62a7f45682b0 | PubMed:21285256
    • Clayton, P., Gault, J. E., Perry, R. J., Cole, T. J., Casey, S., Paterson, W. F., ... Donaldson, M. D. C. (2011). Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: Randomised, double blind, placebo controlled trial. BMJ, 342(7803), [d1980]. DOI: 10.1136/bmj.d1980. Publication link: d97602d6-a083-422f-9adb-dbac9206e343 | PubMed:21493672
    • Gardner, C. J., Robinson, N., Meadows, T., Wynn, R., Will, A., Mercer, J., ... Clayton, P. E. (2011). Growth, final height and endocrine sequelae in a UK population of patients with Hurler syndrome (MPS1H). Journal of Inherited Metabolic Disease, 34(2), 489-497. DOI: 10.1007/s10545-010-9262-8. Publication link: 0d3a8bcd-555d-42d4-9eef-24bc141753f2 | PubMed:21253827
    • Hanson, D., Murray, P. G., Black, G. C. M., & Clayton, P. E. (2011). The genetics of 3-M syndrome: Unravelling a potential new regulatory growth pathway. Hormone Research in Paediatrics, 76(6), 369-378. DOI: 10.1159/000334392. Publication link: 7e1ad46e-1601-4e92-a5d6-bae6d50e9f6b | PubMed:22156540
    • Hanson, D., Murray, P. G., O'Sullivan, J., Urquhart, J., Daly, S., Bhaskar, S. S., ... Black, G. C. M. (2011). Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth. American Journal of Human Genetics, 89(1), 148-153. DOI: 10.1016/j.ajhg.2011.05.028. Publication link: 9a94bfe2-5da8-4b7c-af35-2fe7571a92b1 | PubMed:21737058
    • Mccabe, M., McCabe, M. G., Bäcklund, L. M., Leong, H. S., Ichimura, K., & Collins, V. P. (2011). Chromosome 17 alterations identify goodrisk and poor-risk tumors independently of clinical factors in medulloblastoma. Neuro-Oncology, 13(4), 376-383. DOI: 10.1093/neuonc/noq192. Publication link: 1313c02e-07ae-4ad6-b4fe-af434eceaa30 | PubMed:21292688
    • Patel, L., Chandrashekhar, S. R., Gemmell, I., O'Shea, E., Jones, J., Banerjee, I., ... Clayton, P. (2011). Gender dichotomy in long term growth trajectories of children with 21-hydroxylase deficiency congenital adrenal hyperplasia. Hormone Research in Paediatrics, 75(3), 206-212. DOI: 10.1159/000320700. Publication link: 02908c12-5dd4-45ac-bcf1-fd327c6e0fce | PubMed:20962509
    • Powell, P. D., Bellanné-Chantelot, C., Flanagan, S. E., Ellard, S., Rooman, R., Hussain, K., ... Cosgrove, K. E. (2011). In vitro recovery of ATP-sensitive potassium channels in β-cells from patients with congenital hyperinsulinism of infancy. Diabetes, 60(4), 1223-1228. DOI: 10.2337/db10-1443. Publication link: ab076868-976b-4a9f-9e59-12e2d715cc69 | PubMed:21411514
    • Sarrab, R. M., Lennon, R., Ni, L., Wherlock, M. D., Welsh, G. I., & Saleem, M. A. (2011). Establishment of conditionally immortalized human glomerular mesangial cells in culture, with unique migratory properties. American Journal of Physiology - Renal Physiology, 301(5), F1131-F1138. DOI: 10.1152/ajprenal.00589.2010. Publication link: 7d0f41ca-8b85-4cf1-a4f0-20ac117d9da2 | PubMed:21653636
    • Weber, S., Thiele, H., Mir, S., Toliat, M. R., Sozeri, B., Reutter, H., ... Woolf, A. S. (2011). Muscarinic acetylcholine receptor m3 mutation causes urinary bladder disease and a prune-belly-like syndrome. American Journal of Human Genetics, 89(5), 668-674. DOI: 10.1016/j.ajhg.2011.10.007. Publication link: 0bf7f33c-0436-46bf-8a4d-ef8433120bc6 | PubMed:22077972
    • Westwood, M., Tajbakhsh, S. H., Siddals, K. W., Whatmore, A. J., & Clayton, P. E. (2011). Reduced pericellular sensitivity to IGF-I in fibroblasts from girls with Turner syndrome: A mechanism to impair clinical responses to GH. Pediatric Research, 70(1), 25-30. DOI: 10.1203/PDR.0b013e31821b570b. Publication link: a2808aee-5b60-483c-8240-785a422a4d24 | PubMed:21430600
  • 2010

    Article

    • Malinowska, M., Wilkinson, F. L., Langford-Smith, K. J., Langford-Smith, A., Brown, J. R., Crawford, B. E., ... Bigger, B. W. (2010). Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease. PLoS ONE, 5(12), [e14192]. DOI: 10.1371/journal.pone.0014192. Publication link: 69b65744-9a91-4fea-ac68-0930103f73f7 | PubMed:21152017
  • 2009

    Article

    • Lennon, R., Welsh, G. I., Singh, A., Satchell, S. C., Coward, R. J., Tavaré, J. M., ... Saleem, M. A. (2009). Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1. Diabetologia, 52(9), 1944-1952. DOI: 10.1007/s00125-009-1423-7. Publication link: 5e999a62-ca65-4076-9f8d-d0d70ac9d86c
    • Wynn, R. F., Wraith, J. E., Mercer, J., O'Meara, A., Tylee, K., Thornley, M., ... Bigger, B. W. (2009). Improved Metabolic Correction in Patients with Lysosomal Storage Disease Treated with Hematopoietic Stem Cell Transplant Compared with Enzyme Replacement Therapy. Journal of Pediatrics, 154(4), 609-611. DOI: 10.1016/j.jpeds.2008.11.005. Publication link: b3b9d7b3-4a2c-4aa3-974c-9b7b0c0cb6a5 | PubMed:19324223
  • 2008

    Article