Phototherapy and photodynamic therapy

The group has an active interest in the photoadaptation conferred by ultraviolet exposure and in the underlying mechanisms.

The group is also active in producing guideline reports in phototherapy, through the medium of the British Photodermatology Group.

Photodynamic therapy (PDT) is a non-invasive treatment, involving light activation of a photosensitiser in the skin, which is successful in the treatment of malignant and non-malignant skin disorders. Lesley Rhodes, is exploring the mediation of its effects through a range of techniques including:

  • Dermal microdialysis and immunohistochemical assessment
  • Evaluating potential use of auxiliary treatments
  • Examining the potential, and mechanisms, of PDT-augmented wound healing

Additionally, the group performs a range of clinical trials, including randomised assessment of PDT against alternative treatments, and develops guideline reports.

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