Immunology

The hair follicle is immunologically very interesting, since it, e.g., is a frequent target of autoimmune responses and contains immunologically privileged tissue compartments (whose immune privilege appears to be maintained in part by intrafollicular generated neurohormones such as α-MSH and CGRP). The hair follicle also displays a rich and complex innate immune signalling system, and is highly susceptible to stress-induced neurogenic inflammation.

The group further dissects these - both fundamentally and clinically important - aspects of hair follicle immunology (in particular with reference to alopecia areata and cicatrial alopecias) that await to be fully appreciated as unconventional, yet instructive and physiological relevant a model of general importance for addressing key questions in immunology.