Biomechanics of matrix components

The mechanical properties of most tissues, including skin, are dominated by material that lies outside the cells, the extracellular matrix. This matrix relies on collagens for strength and elastic fibres, which are composed of two proteins elastin and fibrillin, for elasticity.

This research area employs micro-mechanical techniques (operating at the length scale of cells and fibres) and nano-mechanical techniques (operating at molecular length scales) to characterise the mechanical properties of young, aged and diseased skin.